Kim Boekelheide, Ph.D., M.D.- Professor, Pathology and Laboratory Medicine, Brown University

Kim’s laboratory uses many basic techniques in biochemistry and molecular and cell biology to investigate interdisciplinary problems in reproductive toxicology/biology. A major issue in environmental health is mixed exposures. The group uses prototypal cell-type specific testicular toxicants to dissect interactions and inter-dependencies among those cells responsible for successful spermatogenesis. Ongoing experiments evaluate the potential roles of local paracrine growth and death factors in the regulation of spermatogenesis following injury. Knockout and transgenic mice are used to investigate these growth and death factor pathways.